NSJ Bioreagents

PDHA1 Antibody / Pyruvate Dehydrogenase E1 Alpha

Product Code:
 
NSJ-RQ5240
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
AODI-16
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the PDHA1 antibody at -20°C.
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Western blot testing of human HeLa cell lysate with PDHA1 antibody. Predicted molecular weight ~43 kDa.
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Western blot testing of human HeLa cell lysate with PDHA1 antibody. Predicted molecular weight ~43 kDa.

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NSJ-RQ5240-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the PDHA1 antibody should be determined by the researcher.
Description:
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human Pdh E1 Alpha / PDHA1 was used as the immunogen for the PDHA1 antibody.
Limitation:
This PDHA1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P08559