Further Information
DDR1, Cell adhesion kinase, CD167, CD167a antigen, EDDR1, ENTRK4, Mammary carcinoma kinase 10, MCK10, NEP, PTK3, PTK3A, RTK6, Tyrosine-protein kinase CAK, CAK, DDR, Discoidin domain receptor 1, HGK2, MCK-10, NTRK4, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, TRKE, Tyrosine kinase DDR
WB: 1:1000 - 1:2000
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 290-420 of human DDR1 (NP_054700.2).
780
discoidin domain receptor tyrosine kinase 1
DDR1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 125kDa
Affinity purification
Cancer, Immunology, Neuroscience, Signal Transduction
Q08345
Optimal dilutions for each application to be determined by the researcher.