Further Information
CYP26B1, cytochrome P450, family 26, subfamily B, polypeptide 1, CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2, cytochrome P450 retinoid metabolizing protein, subfamily b, retinoic acid-metabolizing cytochrome , P450RAI2
WB: 1:500 - 1:2000
This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 213-512 of human CYP26B1 (NP_063938.1).
56603
cytochrome P450, family 26, subfamily B, polypeptide 1
CYP26B1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 58-65kDa
Affinity purification
Cancer, Chemokines & Cytokines, Immunology, Signal Transduction
Q9NR63
Optimal dilutions for each application to be determined by the researcher.