Further Information
SDC1, syndecan 1, CD138, SDC, SYND1, syndecan, CD138 antigen, heparan sulfate proteoglycan fibroblast growth factor receptor, syndecan proteoglycan 1, syndecan-1
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human SDC1 (NP_002988.3).
6382
syndecan 1
SDC1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 32kDa
Affinity purification
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell
P18827
Optimal dilutions for each application to be determined by the researcher.
