Further Information
7TM receptor, cholinergic receptor, muscarinic 2, CHRM2, FLJ43243, HM2, MGC120006, MGC120007, muscarinic acetylcholine receptor M2, muscarinic M2 receptor, OTTHUMP00000208393, OTTHUMP00000208394, OTTHUMP00000208395, OTTHUMP00000208396
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 208-388 of human CHRM2 (NP_001006629.1).
1129
cholinergic receptor, muscarinic 2
CHRM2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 52kDa
Affinity purification
Neuroscience, Signal Transduction
P08172
Optimal dilutions for each application to be determined by the researcher.