Further Information
PLCG2, FCAS3, Phospholipase C-gamma-2, PLCG 2, PLC-IV, APLAID, Phospholipase C-IV, PLC-gamma-2
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:20 - 1:100
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLCG2 (NP_002652.2).
5336
phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCG2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 175kDa
Affinity purification
Cancer, Cell Cycle, Immunology, Signal Transduction
P16885
Optimal dilutions for each application to be determined by the researcher.
