Further Information
AKR1C4, aldo-keto reductase family 1, member C4, HGNC:387, 3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581, 3-alpha hydroxysteroid dehydrogenase, type I, 3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4, 3-alpha-hydroxysteroid dehydrogenase variant, chlordecone reductase, dihydrodiol dehydrogenase 4, dihydrodiol dehydrogenase isozyme DD4, type I 3-alpha-hydroxysteroid dehydrogenase
WB: 1:500 - 1:2000
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C4 (NP_001809.3).
1109
aldo-keto reductase family 1, member C4
AKR1C4
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 37kDa
Affinity purification
Cancer, Signal Transduction
P17516
Optimal dilutions for each application to be determined by the researcher.