Further Information
CDH11, osteoblast cadherin, OSF-4, OB-cadherin, OB, CDHOB, cadherin-11, cadherin 11, type 2, OB-cadherin (osteoblast), CAD11
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 637-796 of human CDH11 (NP_001788.2).
1009
cadherin 11, type 2, OB-cadherin (osteoblast)
CDH11
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 120kDa
Affinity purification
Cancer, Cell Cycle, Signal Transduction
P55287
Optimal dilutions for each application to be determined by the researcher.