ProSci

TMC1 Antibody

Product Code:
 
PSI-23-681
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of mouse eye, using TMC1 antibody (23-681) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human prostate using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophagus using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of mouse eye, using TMC1 antibody (23-681) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human prostate using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).

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PSI-23-681-100uL100 uL£565.00
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Further Information

Additional Names:
DFNA36, DFNB11, DFNB7, transmembrane channel-like protein 1, transmembrane cochlear-expressed protein 1, transmembrane, cochlear expressed, 1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human TMC1 (NP_619636.2).
NCBI Gene ID #:
117531
NCBI Official Name:
transmembrane channel like 1
NCBI Official Symbol:
TMC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 88kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q8TDI8
User NOte:
Optimal dilutions for each application to be determined by the researcher.