SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody
Antibody Clonality:
Polyclonal
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
SARS-CoV-2 (COVID-19) NSP13 (Helicase) antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Helicase, Non-structural protein 13, NSP13
IHC: 0.5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP13 antibody can detect 2 ng of free peptide at 1 ?g/mL in ELISA. It can detect SARS-CoV-2 NSP13 recombinant protein by ELISA. All other applications and species not yet tested
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019?20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP13 is a multi-functional protein with a zinc-binding domain in N-terminus displaying RNA and DNA duplex-unwinding activities with 5' to 3' polarity. Activity of Helicase is dependent on magnesium(3,4).
- Gorbalenya. bioRxiv: 2020.
- Hui et al. Int J Infect Dis. 2020;91:264-266.
- Tanner et. al. J.Biol. Chem. 2003;278:39578-39582
SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody is supplied in PBS containing 0.02% sodium azide.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted reactivity based on immunogen sequence: SARS-CoV NSP13 (Helicase) protein: (80%)
Anti-SARS-CoV-2 (COVID-19) NSP13 (Helicase) antibody (9181) was raised against a peptide corresponding to 19 amino acids near the carboxyl terminus of the SARS-CoV-2 (COVID-19) NSP13 (Helicase) protein.
The immunogen is located in the last 50 amino acids of SARS-CoV-2 (COVID-19) NSP13 (Helicase).
43740578
ORF1a polyprotein;ORF1ab polyprotein
ORF1ab
Severe acute respiratory syndrome coronavirus 2
Liquid
YP_009725308.1
1802476816
SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody is affinity chromatography purified via peptide column.
Infectious Disease,COVID-19
P0DTC1
Optimal dilutions for each application to be determined by the researcher.