NSJ Bioreagents

Alpha Catenin Antibody

Product Code:
 
NSJ-V3202
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
1G5
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
 
Store the Alpha Catenin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 2
Western blot testing of human 1) A431 and 2) MCF7 cell lysate with Alpha Catenin antibody (clone 1G5). Expected molecular weight ~102 kDa.~
2 / 2
SDS-PAGE Analysis of Purified, BSA-Free Alpha Catenin Antibody (clone 1G5). Confirmation of Integ
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Western blot testing of human 1) A431 and 2) MCF7 cell lysate with Alpha Catenin antibody (clone 1G5). Expected molecular weight ~102 kDa.~
SDS-PAGE Analysis of Purified, BSA-Free Alpha Catenin Antibody (clone 1G5). Confirmation of Integ

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CodeSizePrice
NSJ-V3202-20UG20 ug£264.00
Quantity:
NSJ-V3202-100UG100 ug£534.00
Quantity:
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Further Information

Application Details :
Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 0.5-1ug/ml
Application Note:
Optimal dilution of the Alpha Catenin antibody to be determined by the researcher.
Description:
Recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-Catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-Catenin forms a heterodimer with beta-Catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-Catenin also regulates the beta-Catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A human fusion protein was used as the immunogen for the Alpha Catenin antibody.
Limitation:
This Alpha Catenin antibody is available for research use only.
Localization:
Cell surface, cytoplasmic, cell junctions
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P35221