NSJ Bioreagents

MAP4K3 Antibody / MEKKK3 / GLK

Product Code:
 
NSJ-F54521
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
IgM, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
219CT8.3.1
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Aliquot the MAP4K3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 2
IHC testing of FFPE human skeletal muscle tissue with MAP4K3 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.~
2 / 2
Western blot testing of human 1) HepG2 and 2) MCF7 cell lysate with MAP4K

IHC testing of FFPE human skeletal muscle tissue with MAP4K3 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.~
Western blot testing of human 1) HepG2 and 2) MCF7 cell lysate with MAP4K

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CodeSizePrice
NSJ-F54521-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54521-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE): 1:25
Application Note:
The stated application concentrations are suggested starting points. Titration of the MAP4K3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
Recombinant human protein was used as the immunogen for the MAP4K3 antibody.
Limitation:
This MAP4K3 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
Q8IVH8