NSJ Bioreagents

Cig2 Antibody

Product Code:
 
NSJ-V8291
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
3A11/5
Regulatory Status:
 
RUO
Target Species:
 
Schizosaccharomyces species (bacteria)
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Store the Cig2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
 

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CodeSizePrice
NSJ-V8291-20UG20 ug£264.00
Quantity:
NSJ-V8291-100UG100 ug£534.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
ELISA (order BSA-free format for coating),Western blot: 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Cig2 is a cyclin that functions as the catalytic subunit of cyclin-dependent kinases (Cdks) in the fission yeast Schizosaccharomyces pombe. It is a B-type, S phase cyclin that is required for both the G1/S and G2/M cell cycle transitions and is expressed in a sharp spike that peaks during the G1/S period. Cig2 binds to Cdc2 (Cdk), and the resulting Cdc2/Cig2 complex controls the G1/S transition of the cell cycle. Disruption of Cig2 delays the onset of mitosis. The expression of the Cig2 gene is dependent on Mlu1-binding factor (MBF), and the protein is destroyed during anaphase by the APC/cyclosome (APC/C) and Skp1/Cullin-1/F-box (SCF), thereby ensuring the spike expression pattern of Cig2. SCF regulates Cig2 levels in a dual manner, transcriptionally and post-translationally, while APC/C only destroys the protein.
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Bacterial S. pombe Cig2 purified protein was used as the immunogen for the Cig2 antibody.
Limitation:
This Cig2 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Species Reactivity :
Schizosaccharomyces pombe