NSJ Bioreagents

CFTR Antibody / Cystic Fibrosis Transmembrane Regulator

Product Code:
 
NSJ-V3259
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
SPM176
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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IHC testing of FFPE human pancreas with CFTR antibody (clone SPM176). HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.
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IHC testing of FFPE human pancreas with CFTR antibody (clone SPM176). HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.

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CodeSizePrice
NSJ-V3259-20UG20 ug£264.00
Quantity:
NSJ-V3259-100UG100 ug£534.00
Quantity:
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Further Information

Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.
Description:
Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Gene ID #:
1080
Immunogen:
Human partial recombinant protein was used as the immunogen for this CFTR antibody.
Limitation:
This CFTR antibody is available for research use only.
Localization:
Cell surface, cytoplasmic
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P13569