NSJ Bioreagents

JNK Antibody

Product Code:
 
NSJ-F50464
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot the JNK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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JNK1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue.
2 / 3
Confocal immunofluorescent analysis of JNK1 antibody with HepG2 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
3 / 3
Western blot analysis of MAPK8/ JNK1 antibody and HL-60 (UV-treated) cell lysate.
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JNK1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue.
Confocal immunofluorescent analysis of JNK1 antibody with HepG2 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
Western blot analysis of MAPK8/ JNK1 antibody and HL-60 (UV-treated) cell lysate.

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CodeSizePrice
NSJ-F50464-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50464-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the JNK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 358-389 from the human protein was used as the immunogen for this JNK antibody.
Limitation:
This JNK antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Rat
Uniprot #:
P45983