NSJ Bioreagents

Anti-p21 Antibody

Product Code:
 
NSJ-F52199
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the anti-p21 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Anti-p21 antibody western blot analysis in mouse NIH3T3 lysate
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Anti-p21 antibody western blot analysis in mouse NIH3T3 lysate

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CodeSizePrice
NSJ-F52199-0.08ML0.08 ml£260.00
Quantity:
NSJ-F52199-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the anti-p21 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 126-154 from the mouse protein was used as the immunogen for this anti-p21 antibody.
Limitation:
This anti-p21 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse
Uniprot #:
P39689