NSJ Bioreagents

HIPPI Antibody

Product Code:
 
NSJ-F54213
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the HIPPI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of human 1) brain and 2) lung lysate with HIPPI antibody at 1:2000. Predicted molecular weight: ~49 kDa.
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Western blot testing of human 1) brain and 2) lung lysate with HIPPI antibody at 1:2000. Predicted molecular weight: ~49 kDa.

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CodeSizePrice
NSJ-F54213-0.05ML0.05 ml£260.00
Quantity:
NSJ-F54213-0.2ML0.2 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Western Blot: 1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the HIPPI antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 159-193 from the human protein was used as the immunogen for the HIPPI antibody.
Limitation:
This HIPPI antibody is available for research use only.
Purity:
Peptide affinity purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Bovine
Uniprot #:
Q9NWB7