NSJ Bioreagents

Retinal guanylyl cyclase 1 Antibody / GUCY2D

Product Code:
 
NSJ-F54602
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Aliquot the Retinal guanylyl cyclase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 4
IHC testing of FFPE human thyroid tissue with Retinal guanylyl cyclase 1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
2 / 4
Western blot testing of rat eyeball tissue lysate with Retinal guanylyl cyclase 1 antibody. Predicted molecular weight ~120 kDa.
3 / 4
Western blot testing of human Ramos cell lysate with Retinal guanylyl cyclase 1 antibody. Predicted molecular weight ~120 kDa.
4 / 4
Flow cytometry testing of fixed and permeabilized human HeLa cells with Retinal guanylyl cyclase 1 antibody; Blue=isotype control, Green= Retinal guanylyl cyclase 1 antibody.
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IHC testing of FFPE human thyroid tissue with Retinal guanylyl cyclase 1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of rat eyeball tissue lysate with Retinal guanylyl cyclase 1 antibody. Predicted molecular weight ~120 kDa.
Western blot testing of human Ramos cell lysate with Retinal guanylyl cyclase 1 antibody. Predicted molecular weight ~120 kDa.
Flow cytometry testing of fixed and permeabilized human HeLa cells with Retinal guanylyl cyclase 1 antibody; Blue=isotype control, Green= Retinal guanylyl cyclase 1 antibody.

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CodeSizePrice
NSJ-F54602-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54602-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE): 1:25, Flow cytometry: 1:25 (1x10e6 cells)
Application Note:
The stated application concentrations are suggested starting points. Titration of the Retinal guanylyl cyclase 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 540-570 from the human protein was used as the immunogen for the Retinal guanylyl cyclase 1 antibody.
Limitation:
This Retinal guanylyl cyclase 1 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Antigen affinity purified
Species Reactivity :
Human, Rat
Uniprot #:
Q02846