NSJ Bioreagents

MAL Antibody / Myelin and lymphocyte protein

Product Code:
 
NSJ-RQ6195
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the MAL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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Western blot testing of human 1) Jurkat, 2) Raji and 3) HL60 cell lysate with MAL antibody. Predicted molecular weight ~17 kDa.
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Western blot testing of human 1) Jurkat, 2) Raji and 3) HL60 cell lysate with MAL antibody. Predicted molecular weight ~17 kDa.

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NSJ-RQ6195-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 1-2ug/ml
Application Note:
Optimal dilution of the MAL antibody should be determined by the researcher.
Description:
Myelin and lymphocyte protein is a protein that in humans is encoded by the MAL gene. The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids HAVFSLIRWKSS from the human protein were used as the immunogen for the MAL antibody.
Limitation:
This MAL antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P21145