NSJ Bioreagents

CD46 Antibody

Product Code:
 
NSJ-RQ5487
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
AEI-3
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store the CD46 antibody at -20oC.
1 / 2
Western blot testing of human K562 cell lysate with CD46 antibody. Observed molecular weight: 41~70 kDa depending on glycosylation level.
2 / 2
IHC staining of FFPE human colon tissue with CD46 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
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Western blot testing of human K562 cell lysate with CD46 antibody. Observed molecular weight: 41~70 kDa depending on glycosylation level.
IHC staining of FFPE human colon tissue with CD46 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.

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NSJ-RQ5487-100ul100 ul£535.00
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Further Information

Application Details :
Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:50-1:200
Application Note:
Optimal dilution of the CD46 antibody should be determined by the researcher.
Description:
The protein encoded by the CD46 gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human CD46 was used as the immunogen for the CD46 antibody.
Limitation:
This CD46 antibody is available for research use only.
Localization:
Plasma membrane
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P15529