TargetMol

Gomisin J

Product Code:
 
TAR-T3904
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3904-1mg1mg£102.00
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TAR-T3904-2mg2mg£118.00
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TAR-T3904-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T3904-5mg5mg£168.00
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TAR-T3904-10mg10mg£230.00
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TAR-T3904-25mg25mg£349.00
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TAR-T3904-50mg50mg£485.00
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TAR-T3904-100mg100mg£662.00
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This product comes from: United States.
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Further Information

Bioactivity:
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells.
CAS:
66280-25-9
Formula:
C22H28O6
Molecular Weight:
388.46
Pathway:
Metabolism; PI3K/Akt/mTOR signaling; Membrane transporter/Ion channel; Chromatin/Epigenetic
Purity:
0.9959
SMILES:
COc1c(O)cc2C[C@H](C)[C@H](C)Cc3cc(O)c(OC)c(OC)c3-c2c1OC
Target:
Calcium Channel; AMPK

References

Kim M, et al. Gomisin J Inhibits Oleic Acid-Induced Hepatic Lipogenesis by Activation of the AMPK-Dependent Pathway and Inhibition of the Hepatokine Fetuin-A in HepG2 Cells. J Agric Food Chem. 2015 Nov 11;63(44):9729-39. Ye BH, et al. Preventive effect of gomisin J from Schisandra chinensis on angiotensin II-induced hypertension via an increased nitric oxide bioavailability. Hypertens Res. 2015 Mar;38(3):169-77.