TargetMol

Escin IB

Product Code:
 
TAR-T5S1389
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S1389-1mg1mg£161.00
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TAR-T5S1389-5mg5mg£297.00
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TAR-T5S1389-10mg10mg£406.00
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TAR-T5S1389-25mg25mg£623.00
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TAR-T5S1389-1mL1 mL * 10 mM (in DMSO)£627.00
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TAR-T5S1389-50mg50mg£839.00
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Further Information

Bioactivity:
Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes the release of PGs.
CAS:
26339-90-2
Formula:
C55H86O24
Molecular Weight:
1131.269
Pathway:
Neuroscience; GPCR/G Protein; Immunology/Inflammation
Purity:
0.9973
SMILES:
[H][C@@]12CC(C)(C)[C@@H](OC(=O)C(C)=C/C)[C@H](OC(C)=O)[C@]1(CO)[C@H](O)C[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@](C)(CO)[C@]3([H])CC[C@@]12C
Target:
5-HT Receptor; NO Synthase

References

Comparative pharmacokinetics and the bioavailability of escin Ib and isoescin Ib following the administration of escin, pure escin Ib and isoescin Ib in rats[J]. Journal of Ethnopharmacology, 2014, 151(2):839-845.