TargetMol

Gossypetin

Product Code:
 
TAR-TN1711
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1711-1mg1mg£262.00
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TAR-TN1711-5mg5mg£547.00
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TAR-TN1711-10mg10mg£751.00
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TAR-TN1711-25mg25mg£1,107.00
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TAR-TN1711-50mg50mg£1,460.00
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This product comes from: United States.
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Further Information

Bioactivity:
Gossypetin has anti-mutagenic, anti-atherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects, it inhibits bone resorption through down-regulating lysosomal cathepsin K activity and autophagy-related protein induction in actin ring-bearing osteoclasts.
CAS:
489-35-0
Formula:
C15H10O8
Molecular Weight:
318.237
Pathway:
Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Purity:
0.98
SMILES:
Oc1ccc(cc1O)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O
Target:
MMP; ATPase; PI3K

References

Xie X, et al. Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo. Cancer Lett. 2019;442:126-136. Samant NP, et al. Gossypetin- based therapeutics for cognitive dysfunction in chronic unpredictable stress- exposed mice. Metab Brain Dis. 2022;37(5):1527-1539. Antika L D, et al. Dietary compound gossypetin inhibits bone resorption through down-regulating lysosomal cathepsin K activity and autophagy-related protein induction in actin ring-bearing osteoclasts. Journal of Functional Foods. 2016;24:390-402. Lin HH. In Vitro and in Vivo Atheroprotective Effects of Gossypetin against Endothelial Cell Injury by Induction of Autophagy. Chem Res Toxicol. 2015;28(2):202-215. Wang L, et al. Gossypetin Inhibits Solar-UV Induced Cutaneous Basal Cell Carcinoma Through Direct Inhibiting PBK/TOPK Protein Kinase. Anticancer Agents Med Chem. 2019;19(8):1029-1036.