TargetMol

Nobiletin

Product Code:
 
TAR-T2834
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2834-5mg5mg£112.00
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TAR-T2834-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T2834-10mg10mg£136.00
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TAR-T2834-25mg25mg£172.00
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TAR-T2834-50mg50mg£208.00
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TAR-T2834-100mg100mg£295.00
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TAR-T2834-200mg200mg£402.00
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TAR-T2834-500mg500mg£623.00
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Quantity:
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Nobiletin is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa).
CAS:
478-01-3
Formula:
C21H22O8
Molecular Weight:
402.399
Pathway:
Metabolism; NF-κb; Apoptosis; Autophagy; Immunology/Inflammation; Proteases/Proteasome
Purity:
0.9888
SMILES:
COc1ccc(cc1OC)-c1cc(=O)c2c(OC)c(OC)c(OC)c(OC)c2o1
Target:
Apoptosis; MMP; Reactive Oxygen Species; ROR; Autophagy

References

1. Murakami A, et al. Cancer Res, 2000, 60(18), 5059-5066. 2. Sato T, et al. Cancer Res, 2002, 62(4), 1025-1029. 3. Whitman SC, et al. Atherosclerosis, 2005, 178(1), 25-32. 4. He B, et al. The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome. Cell Metab. 2016 Apr 12;23(4):610-21.