TargetMol

Velutin

Product Code:
 
TAR-T3816
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3816-25mg25mgEnquire
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TAR-T3816-50mg50mgEnquire
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TAR-T3816-1mg1mg£182.00
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TAR-T3816-5mg5mg£345.00
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TAR-T3816-10mg10mg£470.00
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Further Information

Bioactivity:
Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK phosphorylation. Velutin has anti-inflammatory property. Velutin exhibits the greatest potency among all flavones which reduce TNF-α and IL-6 production.
CAS:
25739-41-7
Formula:
C17H14O6
Molecular Weight:
314.293
Pathway:
NF-κb
Purity:
0.98
SMILES:
COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(OC)c1
Target:
NF-κB

References

Xie C, et al. The a?a? flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-? and IL-6 production through inhibiting NF-?B activation and MAPK pathway. J Nutr Biochem. 2012 Sep;23(9):1184-91.