TargetMol

Kirenol

Product Code:
 
TAR-T4S1943
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T4S1943-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T4S1943-20mg20mg£111.00
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This product comes from: United States.
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Further Information

Bioactivity:
1. Kirenol has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid leukemia K562 cells in vitro. 4. Kirenol is capable of promoting osteoblast differentiation in MC3T3-E1 cells through activation of the BMP and Wnt/β-catenin signaling pathways. 5. Kirenol treatment reduces pro-inflammatory cytokine secretion, increases anti-inflammatory cytokine production, inhibits cell proliferation and induces apoptosis of CII-specific lymphocytes in vitro.
CAS:
52659-56-0
Formula:
C20H34O4
Molecular Weight:
338.488
Pathway:
Cytoskeletal Signaling; Stem Cells
Purity:
0.9964
SMILES:
C[C@@]1(CO)C[C@@H](O)C[C@@]2(C)[C@@H]3CC[C@@](C)(C=C3CC[C@H]12)[C@@H](O)CO
Target:
Wnt/beta-catenin

References

Xiao J , Yang R , Yang L , et al. Kirenol Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Differentiation of Th1 and Th17 Cells and Inducing Apoptosis of Effector T Cells[J]. Scientific Reports, 2015, 5(1):9022.