TargetMol

Neogambogic acid

Product Code:
 
TAR-T5724
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5724-1mg1mg£107.00
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TAR-T5724-5mg5mg£149.00
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TAR-T5724-10mg10mg£189.00
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TAR-T5724-1mL1 mL * 10 mM (in DMSO)£199.00
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TAR-T5724-25mg25mg£270.00
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TAR-T5724-50mg50mg£367.00
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TAR-T5724-100mg100mg£511.00
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Further Information

Bioactivity:
Neogambogic acid , an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.
CAS:
93772-31-7
Formula:
C38H46O9
Molecular Weight:
646.777
Pathway:
Apoptosis; Microbiology/Virology;
Purity:
0.9774
SMILES:
CC(C)=CCCC1(C)CC(O)c2c(O)c3C(=O)C4=CC5CC6C(C)(C)OC(CC=C(/C)C(O)=O)(C5=O)C46Oc3c(CC=C(C)C)c2O1
Target:
Apoptosis; Antibacterial

References

Wang K, Tang Y, Sun M,et al.The mechanism of neogambogic acid-induced apoptosis in human MCF-7 cells[J].Acta Biochim Biophys Sin (Shanghai). 2011 Sep;43(9):698-702. Jin G , Wang F F , Li T , et al. Neogambogic Acid Suppresses Receptor Activator of Nuclear Factor ?B Ligand (RANKL)-Induced Osteoclastogenesis by Inhibiting the JNK and NF-?B Pathways in Mouse Bone Marrow-Derived Monocyte/Macrophages[J]. Medical Science Monitor International Medical Journal of Experimental & Clinical Research, 2018, 24:2569-2577.