TargetMol

Byakangelicol

Product Code:
 
TAR-T6S0077
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T6S0077-50mg50mgEnquire
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TAR-T6S0077-1mg1mg£125.00
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TAR-T6S0077-5mg5mg£201.00
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TAR-T6S0077-10mg10mg£262.00
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TAR-T6S0077-1mL1 mL * 10 mM (in DMSO)£268.00
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TAR-T6S0077-25mg25mg£385.00
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Further Information

Bioactivity:
1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expression and the activity of COX-2 enzyme, thus it may have therapeutic potential as an anti-inflammatory drug on airway inflammation.
CAS:
26091-79-2
Formula:
C17H16O6
Molecular Weight:
316.309
Pathway:
Immunology/Inflammation; Neuroscience
Purity:
0.9955
SMILES:
[H][C@]1(COc2c3occc3c(OC)c3ccc(=O)oc23)OC1(C)C
Target:
COX

References

Lin C H , Chang C W , Wang C C , et al. Byakangelicol, isolated from Angelica dahurica, inhibits both the activity and induction of cyclooxygenase-2 in human pulmonary epithelial cells[J]. Journal of Pharmacy & Pharmacology, 2010, 54(9):1271-1278.