TargetMol

Deoxypodophyllotoxin

Product Code:
 
TAR-TN1087
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1087-1mg1mg£164.00
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TAR-TN1087-5mg5mg£303.00
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TAR-TN1087-1mL1 mL * 10 mM (in DMSO)£326.00
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TAR-TN1087-10mg10mg£470.00
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TAR-TN1087-25mg25mg£707.00
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TAR-TN1087-50mg50mg£938.00
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TAR-TN1087-100mg100mg£1,235.00
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Further Information

Bioactivity:
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities.
CAS:
19186-35-7
Formula:
C22H22O7
Molecular Weight:
398.411
Pathway:
Autophagy; Apoptosis; Cytoskeletal Signaling
Purity:
0.9984
SMILES:
[H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1C2
Target:
Apoptosis; Microtubule Associated; Autophagy

References

Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects.Int J Biochem Cell Biol. 2013 Aug;45(8):1710-9. Kim SH, et al. Deoxypodophyllotoxin induces cytoprotective autophagy against apoptosis via inhibition of PI3K/AKT/mTOR pathway in osteosarcoma U2OS cells. Pharmacol Rep. 2017 Oct;69(5):878-884.