Leinco Technologies

Anti-Human Mitochondria (DISCONTINUED)

Product Code:
 
LEI-M117
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
AE-1
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
 
2-8°C
Storage:
 
For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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LEI-M117-2.0ml2.0 ml£267.00
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This product comes from: US.
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  • Further Information
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Further Information

Conjugate/Tag/Label:
Tissue Culture Supernatant
Format:
Anti-Human Mitochondria is supplied in filtered tissue supernatant (RPMI-1640) pH-7.2 containig 0.09% sodium azide.
Formulation:
Anti-Human Mitochondria is supplied in filtered tissue supernatant (RPMI-1640) pH-7.2 containig 0.09% sodium azide.
Long Description:
In cell biology, a mitochondrion (plural mitochondria) is a membrane-enclosed organelle found in most eukaryotic cells. These organelles range from 1?10 micrometers (um) in size. Mitochondria are sometimes described as "cellular power plants" because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy. In addition to supplying cellular energy, mitochondria are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases and may play a role in the aging process. Several characteristics make mitochondria unique. The number of mitochondria in a cell varies widely by organism and tissue type. Many cells have only a single mitochondrion, whereas others can contain several thousand mitochondria. The organelle is composed of compartments that carry out specialized functions. These compartments or regions include the outer membrane, the intermembrane space, the inner membrane, and the cristae and matrix. In humans, mitochondria contain about 615 distinct types of proteins, depending on the tissue of origin. Although most of a cell's DNA is contained in the cell nucleus, the mitochondrion has its own independent genome. Further, its DNA shows substantial similarity to bacterial genomes.
Target:
Mitochondria

References

1. Oizumi, K. et al. (1997) Br J Haematol. 99(2):415-7. Article Link 2. Ferrara, P. et al. (1996) J Biol Chem. 271(12):6941-6. Article Link 3. Chandler, James P. et al. (2011) Surg Neurol Int. 2:116. PubMed 4. Hashizume, Y. et al. (2000) Acta Neuropathol.99(1):31-8. PubMed 5. Casellas, P. et al. (1999) J Biol Chem. 274(5):2938-52. Article Link