Leinco Technologies

Anti-Human CD28 - Purified in vivo GOLD™ Functional Grade

Product Code:
 
LEI-C2820
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
CD28.2
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Co-stimulation
  • Flow Cytometry
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
  • In Vivo Assay
  • Spatial Biology
Shipping:
 
2-8°C
Storage:
 
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-C2820-1.0mg1.0 mg£175.00
Quantity:
LEI-C2820-5.0mg5.0 mg£380.00
Quantity:
LEI-C2820-25mg25 mg£1,014.00
Quantity:
LEI-C2820-50mg50 mg£1,556.00
Quantity:
LEI-C2820-100mg100 mg£2,159.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Antigen Distribution:
CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
Concentration:
? 2.0 mg/ml
Conjugate/Tag/Label:
Purified in vivo Functional Grade
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Long Description:
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
NCBI Gene:
940
Purity:
?95% monomer by analytical SEC, >95% by SDS Page
Target:
CD28

References

1. Stern, LJ. et al. (2005) Proc Natl Acad Sci U S A.102(10):3744-9 PubMed