MBL

Anti-SLC6A6 (TAUT) (Human) pAb

Product Code:
 
MBL-BMP046
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Immunocytochemistry (ICC)
  • Immunohistochemistry (IHC)
Shipping:
 
4°C
Storage:
 
-20°C
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CodeSizePrice
MBL-BMP04650 ul£323.00
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  • Further Information
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Further Information

Applications:
FCM - 1:200 ICC - 1:200 IHC - 1:5000 (Heat treatment required for paraffin)
Background:
SLC6A6, also known as TAUT, belongs to the neurotransmitter transporter family and transports taurine in a Na + - and Cl ? -dependent manner. Taurine is involved in many important physiological processes, including antioxidation, osmolarity regulation, and proper maintenance of the functions of the liver and skeletal muscles. Since fe tuses and neonates cannot independently synthesize taurine, they depend on taurine supplied through the placenta and breast milk of their mothers for their development. According to a recent report, rat SLC6A6 also appears to transport another neurotransmitter, namely, GABA, across the inner blood-retinal barrier.
Formulation:
50 ul volume of PBS containing50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 6533 Mouse: 21366
Immunogen Translated:
Synthetic peptide derived from human SLC6A6
Reactivity:
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including cerebral cortex by Immunohistochemistry. The reactivity has been confirmed by Immunocytochemistry, and intracellular Flow cytometry to detect the full length of human SLC6A6 transiently expressed in HEK 293T cells.
Shelf Life:
1 year
Source:
This antibody was affinity purified from rabbit serum. The rabbit was immunized with a synthetic peptide derived from human SLC6A6.
Target:
SLC6A6/TUAT

Documents

References

?1) Tomi, M., et al., Biochim. Biophys. Acta. 1778, 2138-2142 (2008) 2) Ito, T., et al., J. Mol. Cell Cardiol. 44, 927-937 (2008) 3) Warskulat, U., et al., Methods Enzymol. 428, 439-458 (2007) 4) Ramamoorthy, S., et al., Biochem. J. 300, 893-900 (1994) 5) Uchida, S., et al., PNAS 89, 8230-8234 (1992)