MBL

Anti-p75NTR (Mouse) mAb

Product Code:
 
MBL-D297-3
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
25-8
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
-20°C
1 / 2
2 / 2
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MBL-D297-3100 ul£296.00
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Further Information

Applications:
FCM - 10 ug/mL (final concentration)
Background:
p75NTR (p75 neurotrophin receptor) as known as LNGFR/p75NGFR/TNFRSF16/NGFR, a member of the TNF receptor superfamily, is a low affinity nerve growth factor receptor. Expression of p75NTR is observed in a number of non-neuronal and neuronal cells including motor neurons during development and also in damaged neurons. It is known that p75NTR/NGF signal transduction involved in both cell survival as well as cell death of neural cells and apoptosis induction of neurons.
Concentration:
1 mg/mL
Formulation:
100 ug IgG in 100 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Immunogen Translated:
Mouse fetal liver cells
Reactivity:
This antibody reacts with mouse p75NTR on Flow cytometry.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma (clone 25-8) supernatant using protein G agarose. This hybridoma was established by fusion of mouse myeloma cell P3X with Wister rat lymphocyte immunized with mouse fetal hepatic cells.
Target:
p75NTR

Documents

References

1) Suzuki, K., et al., Gastroenterology 135, 270-281 (2008) Clone 25-8 is used in this reference.