MBL

Anti-Fc micro R (TOSO/FAIM3) (Mouse) mAb -FITC

Product Code:
 
MBL-D303-4
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
4B5
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
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2 / 2
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MBL-D303-4100 ul£345.00
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Further Information

Applications:
FCM - 10-20 ug/mL (final concentration)
Background:
TOSO/Fas apoptotic inhibitory molecule 3 (FAIM3) was initially identified as an inhibitor for Fas-mediated apoptosis when overexpressed in T cells. The molecule has recently been identified as a Fc receptor for IgM (FcuR) both in humans and mice. FcuR (TOSO/FAIM3) is predominantly expressed in B lymphocyte lineage cells. In humans, FcuR is also expressed on T cells. Chronic lymphocytic leukemia cells are reported to express increased levels of FcuR compared to healthy B cells, and that its expression in the leukemia cells is controlled by B-cell receptor signaling. These observations may suggest a role for FcuR in BCR signaling and/or B-cell activation.
Concentration:
500 ug/mL
Conjugate:
FITC
Formulation:
PBS containing 1% BSA and 0.09% NaN3
Gene IDs:
Mouse: 69169
Shelf Life:
1 year
Source:
Purified IgG from hybridoma supernatant
Target:
FAIM3

Documents