MBL

Anti-HLA-A24 (Human) mAb-FITC

Product Code:
 
MBL-K0208-4
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
17A10
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
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MBL-K0208-4100 uL£280.00
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  • Further Information
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Further Information

Applications:
FCM - 10 ug/mL (final concentration)
Background:
HLA (human leukocyte antigen)-A24 is a class I MHC antigen. HLA-A24 is the most frequent HLA class I molecule in Asian populations, present in approximately ~70% of the Japanese population. HLA-A24 is also found in approximately 35% of the Indian population and 19% of Caucasians. HLA antigens may play a role in genetic susceptibility to disease.
Concentration:
500 ug/ml
Conjugate:
FITC
Formulation:
50 ug IgG in 100 ul volume of PBS containing 1% BSA and 0.09% NaN3.
Gene IDs:
Human: 3105
Immunogen Translated:
Recombinant human HLA-A24
Reactivity:
This antibody reacts with HLA-A24 on Flow cytometry. Note: It was reported that this clone 17A10 cross-reacted to HLA-B27 and some indeterminate HLA. Although HLA-B27 population is so small in Japanese, about 20% of tested population in our laboratories reacted to this antibody as false-positive. To ensure your experiment, you should confirm HLA genotyping.
Shelf Life:
1 year
Source:
This antibody was purified from hybridoma (clone 17A10) supernatant using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell Sp2/0 with C57BL/6 Tg mouse splenocyte immunized with the human recombinant HLA-A24.
Target:
HLA-A24

Documents

References

1) Kozako, T., et al., J. Immunol. 177, 5718-5726 (2006) 2) Lutz, C. T., et al., J. Immunol. 153, 4099-4110 (1994) 3) Tahara, T., et al., Immunogenetics 32, 351-360 (1990) Clone 17A10 is used in these references.