MBL

Anti-Fas (CD95) (Human) mAb-PE

Product Code:
 
MBL-MD-10-5
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
UB2
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Immunohistochemistry (IHC)
Shipping:
 
4°C
Storage:
 
4°C
1 / 2
2 / 2
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
MBL-MD-10-550 Tests£345.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Applications:
FCM - 20 uL IHC - 10-20 ug/mL
Background:
It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas antigen is a cell-surface protein that mediates apoptosis. It is expressed in various tissues including the thymus and has structural homology with a number of cell-surface receptors, including tumor necrosis factor receptor and nerve growth factor receptor.
Conjugate:
PE
Formulation:
50 tests in 1 mL volume of PBS containing 1% BSA and 0.09% NaN3.
Gene IDs:
Human: 355 Mouse: 14102
Immunogen Translated:
Recombinant human Fas
Reactivity:
This antibody recognizes the human Fas antigen specifically. Clone UB2 does not recognize the mouse Fas antigen.
Shelf Life:
1 year
Source:
This antibody was purified from ascites fluid (clone UB2) by ammonium sulfate precipitation and affinity chromatography on protein A agarose. This hybridoma was established by fusion of mouse myeloma cell NS-1 with Balb/c mouse splenocyte immunized with recombinant human Fas.
Target:
Fas

Documents

References

1) Vega, M. I., et al., J. Immunol. 175, 2174-2183 (2005) 2) Mezosi, E., et al., Mol. Endocrinol 19, 804-811(2005) 3) Hauptschein, R., et al., Cancer Res.65, 1887-1896 (2005) 4) Suhara, T., et al., Hypertension 43, 1208-1213 (2004) 5) Suhara, T., et al., Mol. Cell Biol. 22, 680-691 (2002) 6) Shinohara, H., et al., Cancer Res. 60, 1766-1772 (2000) 7) Sata, M., et al., Arterioscler. Thromb. Vasc. Biool.20, 309-316 (2000) 8) Hiromatsu, Y., et al., J. Clin. Endocrinol. Metab. 84, 2896-2902 (1999) 9) Kuwano, K., et al., Am. J. Respir. Cell Mol. Biol. 20, 53-60 (1999) 10) Dai, C. H., et al., Blood 91, 1235-1242 (1998) 11) Ando, K., et al., J. Immunol. 158, 5283-5291 (1997) 12) Boirivant, M., et al., J. Clin. Invest. 98, 2616-2622 (1996) 13) Hata, H., et al., Blood 86, 1939-1945 (1995) 14) Watanabe-Fukunaga, R., Nature 356, 314-317 (1992) 15) Ito, N., et al., Cell 66, 233-243 (1991) 16) Kobayashi, N., et al., PNAS. 87, 9620-9624 (1990) 17) Yonehara, S., et al., J. Exp.Med. 169, 1747-1756 (1989) Clone UB2 is used in reference number 1) - 13).