Elabscience

Perforin Polyclonal Antibody

Product Code:
 
E-AB-65660
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Mouse spleen using Perforin Polyclonal Antibody at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Mouse spleen using Perforin Polyclonal Antibody at dilution of 1:100 (40x lens).

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E-AB-65660-60uL60uL£210.00
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E-AB-65660-120uL120uL£291.00
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E-AB-65660-200uL200uL£431.00
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Further Information

Abbreviation:
Perforin
Background:
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
61kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human Perforin (NP_001076585.1).
ObservedMW:
70kDa
Purification method:
Affinity purification
Target Synonym:
PRF1;FLH2;HPLH2;P1;PFN1;PFP;perforin-1;Perforin
UNIProt ID:
P14222

Documents