Elabscience

PSENEN Polyclonal Antibody

Product Code:
 
E-AB-66448
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using PSENEN Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using PSENEN Polyclonal Antibody at dilution of 1:1000.

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CodeSizePrice
E-AB-66448-60uL60uL£210.00
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E-AB-66448-120uL120uL£291.00
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E-AB-66448-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
PSENEN
Background:
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
12kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human PSENEN (NP_758844.1).
ObservedMW:
16kDa
Purification method:
Affinity purification
Target Synonym:
PSENEN;MDS033;MSTP064;PEN-2;PEN2
UNIProt ID:
Q9NZ42

Documents