Elabscience

HLA-DMB Polyclonal Antibody

Product Code:
 
E-AB-67981
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Raji cells using HLA-DMB Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of Raji cells using HLA-DMB Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-67981-60uL60uL£210.00
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E-AB-67981-120uL120uL£291.00
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E-AB-67981-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
HLA-DMB
Background:
HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
28kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human HLA-DMB
ObservedMW:
29kDa
Purification method:
Affinity purification
Target Synonym:
HLA-DMB;D6S221E;RING7;major histocompatibility complex;class II;DM beta
UNIProt ID:
P28068

Documents