Elabscience

SMAD7 Polyclonal Antibody

Product Code:
 
E-AB-65776
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of SW480 cells using Smad7 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of SW480 cells using Smad7 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-65776-60uL60uL£210.00
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E-AB-65776-120uL120uL£291.00
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E-AB-65776-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
SMAD7
Background:
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
23kDa/46kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant fusion protein of human SMAD7
ObservedMW:
46kDa
Purification method:
Affinity purification
Target Synonym:
SMAD7;CRCS3;MADH7;MADH8
UNIProt ID:
O15105

Documents