Elabscience

RUNX1T1 Polyclonal Antibody

Product Code:
 
E-AB-67119
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using RUNX1T1 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using RUNX1T1 Polyclonal Antibody at dilution of 1:1000.

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CodeSizePrice
E-AB-67119-60uL60uL£210.00
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E-AB-67119-120uL120uL£291.00
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E-AB-67119-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
RUNX1T1
Background:
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
44kDa/48kDa/63kDa/64kDa/67kDa/68kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant fusion protein of human RUNX1T1 (NP_783554.1).
ObservedMW:
67kDa
Purification method:
Affinity purification
Target Synonym:
RUNX1T1;AML1-MTG8;AML1T1;CBFA2T1;CDR;ETO;MTG8;ZMYND2
UNIProt ID:
Q06455

Documents