Elabscience

FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

Product Code:
 
E-AB-F1132C
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b, κ
Antibody Clone:
 
10F.9G2
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD274/PD-L1 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD274/PD-L1 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

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CodeSizePrice
E-AB-F1132C-50Tests50Tests£107.00
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Quantity:
E-AB-F1132C-100Tests100Tests£127.00
Special offer! Buy 2 Get 1 Free on selected Elabscience Flow Cytometry Antibodies. Read more here.
Quantity:
E-AB-F1132C-100Testsx2100Testsx2£153.00
Special offer! Buy 2 Get 1 Free on selected Elabscience Flow Cytometry Antibodies. Read more here.
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD274/PD-L1
Background:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
FITC
GeneID:
60533
Target Synonym:
B7-H1; PD-L1;Programmed cell death ligand 1;B7 homolog 1;B7-H; B7H1; PDL1; PDCD1L1; PDCD1LG1;
UNIProt ID:
Q9EP73
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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