Elabscience

ERH Polyclonal Antibody

Product Code:
 
E-AB-53016
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ERH Polyclonal Antibody at dilution of 1:55(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ERH Polyclonal Antibody at dilution of 1:55(?200)

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E-AB-53016-20uL20uL£125.00
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E-AB-53016-60uL60uL£172.00
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E-AB-53016-120uL120uL£237.00
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E-AB-53016-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
ERH
Background:
ERH (enhancer of rudimentary homolog), also known as DROER, is a 104 amino acid transcriptional coregulator that is ubiquitously expressed and highly conserved among eukaryotes. ERH may play a role in cell cycle regulation and pyrimidine biosynthesis. ERH represses the function of the coactivator PCBD, preventing it from enhancing the activity of the tissue-specific transcription factor HNF-1 (hepatocyte nuclear factor-1). HNF-1 is a homeodomain transcription factor that binds DNA as a dimer and the HNF-1/DNA complex is stabilized by PCBD. By repressing PCBD, ERH disrupts the stability of the HNF-1/DNA complex, affecting the expression of multiple genes in the liver. The structure of ERH is characterized by a single domain consisting of three alpha-helices and four beta-strands. ERH has a long flexible loop that is significantly conserved, suggesting that this loop region may be important for the function of ERH. ERH has two casein kinase II phosphorylation sites that are thought to disrupt the ability of ERH to dimerize.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ERH
Purification method:
Antigen affinity purification
Target Synonym:
DROER;Enhancer of rudimentary homolog (Drosophila);Enhancer of rudimentary homolog;ERH;ERH;FLJ27340;HGNC:3447
UNIProt ID:
P84090

Documents