Elabscience

PCBD1 Polyclonal Antibody

Product Code:
 
E-AB-53015
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:90(?200)
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Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:90(?200)

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E-AB-53015-20uL20uL£125.00
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E-AB-53015-120uL120uL£237.00
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E-AB-53015-200uL200uL£344.00
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Further Information

Abbreviation:
PCBD1
Background:
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
12 kDa
Concentration:
1.62 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:80-1:400, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PCBD1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
4 alpha hydroxy tetrahydropterin dehydratase;4-alpha-hydroxy-tetrahydropterin dehydratase;6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;DCoH;Dimerization cofactor of hepatic nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1-alpha;Dimerization cofactor of HNF1;Dimerizing cofactor for HNF1;PCBD 1;PCBD;PCBD1;PCD;Phenylalanine hydroxylase stimulating protein;Phenylalanine hydroxylase-stimulating protein;PHS;PHS;Pterin 4 alpha carbinolamine dehydratase;Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;Pterin carbinolamine dehydratase;Pterin-4-alpha-carbinolamine dehydratase
UNIProt ID:
P61457

Documents