Elabscience

FNDC3B Polyclonal Antibody

Product Code:
 
E-AB-52260
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(?200)
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Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(?200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(?200)

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E-AB-52260-20uL20uL£125.00
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E-AB-52260-60uL60uL£172.00
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E-AB-52260-120uL120uL£237.00
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E-AB-52260-200uL200uL£344.00
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Further Information

Abbreviation:
FNDC3B
Background:
Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
Purification method:
Antigen affinity purification
Target Synonym:
DKFZp686D14170 ;DKFZp762K137;Factor for adipocyte differentiation 104;FAD104;fibronectin type III domain containing 3B ;FLJ23399;HCV NS5A binding protein 37 ;MGC10002;NS5ABP37;PRO4979;YVTM2421
UNIProt ID:
Q53EP0

Documents