Elabscience

HIPK3 Polyclonal Antibody

Product Code:
 
E-AB-19326
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HIPK3 Polyclonal Antibody at dilution of 1:60(?200)
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HIPK3 Polyclonal Antibody at dilution of 1:60(?200)

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E-AB-19326-20uL20uL£125.00
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E-AB-19326-60uL60uL£172.00
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E-AB-19326-120uL120uL£237.00
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E-AB-19326-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
HIPK3
Background:
Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human HIPK3
Purification method:
Antigen affinity purification
Target Synonym:
Androgen receptor interacting nuclear protein kinase;Androgen receptor-interacting nuclear protein kinase;ANPK;DYRK6;Fas interacting serine/threonine protein kinase;Fas-interacting serine/threonine-protein kinase;FIST;FIST3;Hipk3;HIPK3;homeodomain interacting protein kinase 3;Homeodomain-interacting protein kinase 3;Homolog of protein kinase YAK1;PKY;RP24 297H17.5;YAK1
UNIProt ID:
Q9H422

Documents