Elabscience

TPPP Polyclonal Antibody

Product Code:
 
E-AB-18394
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 2
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TPPP Polyclonal Antibody at dilution of 1:25(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TPPP Polyclonal Antibody at dilution of 1:25(?200)
❮❯

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TPPP Polyclonal Antibody at dilution of 1:25(?200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TPPP Polyclonal Antibody at dilution of 1:25(?200)

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-18394-20uL20uL£125.00
Quantity:
E-AB-18394-60uL60uL£172.00
Quantity:
E-AB-18394-120uL120uL£237.00
Quantity:
E-AB-18394-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
TPPP
Background:
Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
24 kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
25 kDa brain specific protein ;25 kDa brain-specific protein;Brain specific protein p25 alpha;Glycogen synthase kinase 3 (GSK3) inhibitor p24;OTTHUMP00000161630;p24;p25;p25-alpha;p25alpha ;TPPP;TPPP/p25;TPPP;TPPP1;Tubulin polymerization promoting protein;Tubulin polymerization-promoting protein
UNIProt ID:
O94811

Documents