Elabscience

ATF6B Polyclonal Antibody

Product Code:
 
E-AB-18330
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of Mouse liver tissue Hela cell Human testis tissue Jurkat and HEPG2 cell lysates using ATF6B Polyclonal Antibody at dilution of 1:300
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ATF6B Polyclonal Antibody at dilution of 1:30(?200)
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Western blot analysis of Mouse liver tissue Hela cell Human testis tissue Jurkat and HEPG2 cell lysates using ATF6B Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ATF6B Polyclonal Antibody at dilution of 1:30(?200)

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E-AB-18330-20uL20uL£125.00
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E-AB-18330-200uL200uL£344.00
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  • Further Information
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Further Information

Abbreviation:
ATF6B
Background:
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
77 kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ATF6B
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ATF6B;CREBL1;G13;Cyclic AMP-dependent transcription factor ATF-6 beta;cAMP-dependent transcription factor ATF-6 beta;Activating transcription factor 6 beta;ATF6-beta;Protein G13;cAMP response element-binding protein-related protein;
UNIProt ID:
Q99941

Documents

References

  • https://www.degruyter.com/view/journals/tjb/44/5/article-p599.xml