Elabscience

TDG Polyclonal Antibody

Product Code:
 
E-AB-64285
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Mouse brain using TDG Polyclonal Antibody.
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Western blot analysis of extracts of Mouse brain using TDG Polyclonal Antibody.

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CodeSizePrice
E-AB-64285-60uL60uL£210.00
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E-AB-64285-120uL120uL£291.00
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E-AB-64285-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
TDG
Background:
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
46kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human TDG (NP_003202.3).
ObservedMW:
60kDa
Purification method:
Affinity purification
Target Synonym:
TDG;hTDG
UNIProt ID:
Q13569

Documents