Elabscience

RNASEH2A Polyclonal Antibody

Product Code:
 
E-AB-65212
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using RNASEH2A Polyclonal Antibody at dilution of 1:1000.
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Immunofluorescence analysis of C6 cells using RNASEH2A Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.

Western blot analysis of extracts of various cell lines using RNASEH2A Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of C6 cells using RNASEH2A Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.

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CodeSizePrice
E-AB-65212-60uL60uL£210.00
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E-AB-65212-120uL120uL£291.00
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E-AB-65212-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
RNASEH2A
Background:
The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
33kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human RNASEH2A (NP_006388.2).
ObservedMW:
33kDa
Purification method:
Affinity purification
Target Synonym:
RNASEH2A;AGS4;JUNB;RNASEHI;RNHIA;RNHL
UNIProt ID:
O75792

Documents